Vicinal Stereocenter Construction via α-Boryl Carbanions from Borylated Cyclopropanes
The Technion – Israel Institute of Technology Professor Ilan Marek’s team utilized α-boryl carbanion intermediates as a platform for stereochemical generation, exploring the complex behavior of α-boryl carbanions generated from various cyclopropyl boronic methyl iodides in selective ring-opening and electrophilic reactions, conducting a series of highly stereoselective nucleophilic substitution reactions to construct vicinal stereocenters. Abstract … Read more