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Research has found that for certain iodides, some phosphine-free ligand catalysts can efficiently catalyze reactions under milder conditions, such as PdCl2, Pd(OAc)2, Pd/C, etc. At the same time, it can also avoid the impurities formed by ligands during the reaction that complicate the product separation process. Hiroa【Sakurai, H. J. Org. Chem. 2002, 67, 2721】 and … Read more