Discovery of an Unconventional Lamprey Lymphocyte Lineage Highlights Divergent Features in Vertebrate Adaptive Immune System Evolution

Discovery of an Unconventional Lamprey Lymphocyte Lineage Highlights Divergent Features in Vertebrate Adaptive Immune System Evolution

Journal: Nature Communications Impact Factor: 14.7 Main Technology:scRNA-seq Introduction Lymphocyte receptors have evolved independently in jawed and jawless vertebrates, exhibiting similar adaptive immune responses. However, the functional subtypes and molecular diversity of lymphocytes in jawless vertebrates remain poorly defined compared to jawed animals. The authors analyzed the gills, intestines, and blood of the lamprey (Lampetra … Read more