Breakthrough in C–H Borylation of Aliphatic Amines: Metal-Free Catalysis Achieves Selective Functionalization at β/γ Positions
Image source: J. Am. Chem. Soc.Introduction: Professor Vladimir Gevorgyan has developed a mild, light-induced, metal-free method for the borylation of β and γ C–H bonds in amines. This method employs a regioselective intramolecular hydrogen atom transfer (HAT) process, successfully obtaining key aminobutyl radical intermediates through commercially available removable iodinated aromatic chains. Notably, this method introduces … Read more