Efficient Synthesis of N-Alkyl or N-Aryl Nitrogen-Containing Propanes via α and β Nucleophilic Additions
The team of Wenbo Liu and Quanbin Jiang from Sun Yat-sen University achieved the efficient transformation of conjugated hydroxamic acids into redox-neutral nitrogen-containing propanes through nucleophilic α and β addition strategies. It is noteworthy that electron-rich anilines, such asN,N–dimethylaminoaniline and4-methoxyaniline, can directly serve as nitrogen atom donors in the nitrogenation process. The success of this … Read more